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  • Publications:

    Science & Medicine

    • Management of postoperative inflammation after cataract and complex ocular surgeries: a systematic review and Delphi survey. Aptel F; OSIRIS group et al., Br J Ophthalmol. 2017 Nov;101(11):1-10.
    • Postoperative Ocular Inflammation: A Single Subconjunctival Injection of XG-102 Compared to Dexamethasone Drops in a Randomized Trial. Chiquet C. et al., Am J Ophthalmol. 2017 Feb;174:76-84
    • Sub-conjunctival  injection of  XG-102, a c-Jun N-Terminal Kinase inhibitor peptide in the treatment of endotoxin-induced uveitis in rats. Journal of Ocular  Pharmacology and Therapeutics 2014.El Zaoui et al.
    • Sub-conjunctival injection of  XG-102, a JNK inhibitor peptide, in patients with  intraocular inflammation: A safety and tolerability study. Journal of Ocular Pharmacology and Therapeutics. Beydoun et al
    • XG-102 administered to healthy male volunteers as a single intravenous infusion: a randomized, double-blind, placebo-controlled, dose-escalating study. Pharmacology Research & Perspectives 2014. Deloche et alLink to publication. 
    • An azabisphosphonate-capped poly(phosphorhydrazone) dendrimer for the treatment of endotoxin-induced-uveitis. Molecules 2013. Fruchon et  al. Link to publication.
    • Ocular distribution, Spectrum of activity, and in vivo viral neutralization of a fully humanized anti-herpes simplex virus IgG Fab fragment following topical  application. AAC 2011. Berdugo et al. PMID: 22203590
    • A peptide inhibitor of c-Jun N-terminal kinase for the treatment of endotoxin-induced uveitis. IOVS 2010. Touchard et al. PMID: 20393119

    Science & Environment

    • Maitriser la renouee du Japon en zones humides. Tissut M. et al., Phytoma 711, 2018
    • Maitriser la renouee du Japon et les especes voisines. Fondements  Theoriques et Techniques. Barber M. et al, Phytoma, 682, 2015


    • Poster, EAU17, London  24-28 March 2017: Effect of Brimapitide on acute and chronic cystitis  model induced by cyclophosphamide in conscious rats. Abadie et al. rn
    • Poster, 53em ERA-EDTA Congress, May 21-24 2016, Vienna: Effects of JNK inhibitor on Puromycin  aminonucleoside-Induced nephropathy in rats. Alfarano et al.
    • Poster, 53em ERA-EDTA Congress, May 21-24 2016, Vienna: Effects of JNK inhibitor in a rat model of ischemia-reperfusion injury. Alfarano et al.
    • Poster, ARVO Meeting May  5-9 2013: Tolerance of a sub-conjunctival injection of a 31 D-amino  acids JNK inhibitor peptide (XG-102) in ocular inflammation. Beydoun et    al.
    • Poster, ISOPT Meeting March 7-10 2013: Tolerance of a sub-conjunctival injection of XG-102 in ocular inflammation. Beydoun et al.
    • Oral communication, IOIS Meeting November 2011: XG-102, A JNK inhibitor peptide for thern treatment of intraocular inflammation: from the concept to drug development. J-M Combette.
    • Poster, ARVO Meeting April  2010, Ocular  distribution, spectrum of activity, and in vivorn viral neutralization of a fully humanized anti-herpes simplex virus IgG  Fab fragment following  topical application. 2010. Berdugo et al.
    • Poster, ARVO Meeting April  2009, Ocular  Penetration and Biodistribution of Ac8, a Fully  Human IgG Fab Fragment Neutralizing Hsv1 and Hsv2, After Topical Instillation on the Rat Eye. Combette et al.


    • 3 patents filed in 2011
    • 3 patents filed in 2012
    • 2 patents filed in 2013
    • 2 patents filed in 2014
    • 2 patents filed in 2015
    • 2 patents filed in 2016
    • 1 patent filed in 2017